Bydureon

What is Bydureon?

is an extended release injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Bydureon is a long-acting form of exenatide.

Bydureon is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.

This medication guide provides information about the Bydureon brand of exenatide. Byetta is another brand of exenatide that is not covered in this medication guide.

Important information

You should not use Bydureon if you have severe kidney disease (or you are on dialysis), slowed digestion, diabetic ketoacidosis, a personal or family history of thyroid cancer, or if you have a type of cancer called multiple endocrine neoplasia type 2 (MEN 2).

Stop using Bydureon and call your doctor at once if you have severe pain in your upper stomach spreading to your back, with nausea, vomiting, and a fast heart rate. These could be symptoms of pancreatitis.

Do not use Bydureon to treat type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Bydureon is an extended-release form of exenatide administered as an injection once every seven days. The dose can be administered at any time of day, with or without meals. Follow your doctor’s instructions.

Before taking this medicine

You should not use Bydureon if you are allergic to exenatide, or if you have:

• severe kidney disease (or if you are on dialysis);
• a severe stomach disorder that causes slow digestion;
• diabetic ketoacidosis (call your doctor for treatment with insulin);
• a personal or family history of thyroid cancer; or
• multiple endocrine neoplasia type 2 (MEN 2, a cancer that can affect the thyroid, parathyroid, and adrenal glands).

To make sure this medicine is safe for you, tell your doctor if you have ever had:

• kidney disease, or a kidney transplant;
• problems with digestion;
• pancreatitis or gall stones;
• alcoholism; or
• high triglycerides (a type of fat in blood).

In animal studies, Bydureon caused thyroid tumors. However, very high doses are used in animal studies. It is not known whether these effects would occur in people using doses recommended for human use. Ask your doctor about your personal risk.

It is not known whether Bydureon will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

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